Pan Fried Tilapia Sandwich Recipe -
Pan Fried Tilapia Sandwich Recipe
  • READY IN 20 mins

Pan Fried Tilapia Sandwich

Recipe by  

"Tilapia is grilled with butter, Old Bay seasoning, and garlic, and then set atop toasted multigrain bread with melted pepper jack cheese and a sauce of mayo, dill relish, red onions, tomato, and a piri piri kick."

+ Recipe Box + Shopping List + Menu Print

Ingredients Edit and Save

Original recipe makes 2 sandwiches Change Servings
  • PREP

    10 mins
  • COOK

    10 mins

    20 mins


  1. Stir together the mayonnaise, onion, tomato, relish, and piri piri in a small bowl. Season to taste with salt and pepper, and set aside.
  2. Season the tilapia fillets on both sides with the seafood seasoning and garlic powder. Melt the butter in a skillet over medium heat. Cook the tilapia fillets until they are golden brown on both sides and no longer translucent in the center, 2 to 3 minutes per side. Place two slices of pepperjack cheese on top of each fillet, cover the skillet, and cook until the cheese has melted.
  3. Place each tilapia fillet onto a slice of toasted bread, spread with the reserved sauce, then top with the remaining slices of bread.
Kitchen-Friendly View


  • Cook's Note
  • If you can't find piri piri, use cayenne pepper instead.

Reviews More Reviews

Most Helpful Positive Review
Sep 09, 2010

I didn't make the mayo sauce, and I didn't eat it as a sandwich, but I did season the tilapia fillets with Old Bay and garlic and pan fried them in butter. I poured the butter from the skillet over the fish when I served it. It didn't need any extra sauce as far as I was concerned...delicious as is.

Most Helpful Critical Review
Mar 16, 2009

It was not that good. The recipe calls for way too much cayenne pepper. My husband I were dissapointed in it.


39 Ratings

Feb 27, 2012

I love making this recipe using soft tortillas and eating as fish tacos.

Apr 07, 2010

I made this tonight using some frozen tilapia purchased at a local store. The store packages each fish fillet individually, making this a fantastically easy recipe! I don't really like spicy, so I did not make the sauce. I did use the tomato and mayonnaise on the bread, however. The seasoning for the fish was perfect; I added some salt as well. I don't think it would reheat well, so it will remain a quick dinner or weekend lunch meal. I served it with vegetarian vegetable soup and pickle spears. Fresh fruit for dessert.

Feb 27, 2012

Yum, as one reviewer mentioned, great as fish tacos w/ crispy or flour tortillas. Use olive oil or coconut oil to cook fish and low fat or fat free mayo and Low fat cheese. Tortillas can replace bread or crumble fish in your choice of greens and low-fat dressing for a delish salad. Ask community for suggestions to make dishes more "heart" friendly. We love to share. Thanks Nan13 for sharing a great fish sandwich.

Apr 04, 2011

DELICIOUS!!!!! I can't picture myself ever eating a battered fish sandwich again. Loved the spicy "kick", the freshness of the tilapia and the "out of this world" salsa. YUM!

Oct 11, 2010

My husband and I loved this! We didn't have all the ingredients on hand (tomatoes, chopped onion, pepperjack cheese), however, it was still very good. This was also something quick to whip up for lunch. Definately adding to our weekly rotation.

Jan 11, 2012

very good. it's nothing outstanding, but i will make it again. the sauce is good, but the tomatos and onions make the sauce a little too chunky for me. will seperate from the sauce next time. thanks!


Rate This Recipe

Glad you liked it! Your friends will, too:


  • Calories
  • 798 kcal
  • 40%
  • Carbohydrates
  • 31.5 g
  • 10%
  • Cholesterol
  • 143 mg
  • 48%
  • Fat
  • 55.3 g
  • 85%
  • Fiber
  • 5.4 g
  • 21%
  • Protein
  • 43.7 g
  • 87%
  • Sodium
  • 1501 mg
  • 60%

* Percent Daily Values are based on a 2,000 calorie diet.

See More

About the Cook

Subscribe Today!

In Season

Mealtime Money-Savers
Mealtime Money-Savers

Browse through over 500 recipes for delicious, budget-friendly meals.

Can What You Can't
Can What You Can't

The old saying goes, "Eat what you can, and can what you can't!" We have the know-how.

Subscribe Today! Only $7.99
Subscribe Today! Only $7.99

Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!

Related Videos

Fried Mortadella Sandwich

Raise the fried bologna sandwich to incredible new heights!

Jeannie's Kickin' Fried Fish

A quick and easy recipe for Cajun fried tilapia.

Pan-Seared Tilapia

Discover the delicious and easy way to prepare tilapia.

Recently Viewed Recipes

Argentina  |  Australia & New Zealand  |  Brazil  |  Canada  |  China  |  France  |  Germany  |  India  |  Italy  |  Japan  |  Korea  |  Mexico

Netherlands  |  Poland  |  Quebec  |  Russia  |  SE Asia  |  United Kingdom & Ireland  |  United States