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Garlic Alfredo Tilapia

Make this popular restaurant dish from scratch--it's easy and so tasty. See more

READY IN 25 mins

Garlic Alfredo Tilapia

Read Reviews (236)

"My version of Ruby Tuesday's New Orleans Seafood, minus the shrimp. I merged a few different recipes and came up with this. It comes pretty close! Three fillets are usually enough for my husband, my toddler, and myself. I serve this with rice and steamed broccoli, to really feel like Ruby Tuesday's recipe!" — youngwoman

Ingredients Edit and Save

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Original recipe makes 4 servings Change Servings

4 tilapia fillets
2 tablespoons olive oil
1 tablespoon Creole seasoning, or to taste

3 tablespoons butter
2 cloves garlic, minced
1 cup Alfredo sauce

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Directions

Preheat an oven to 425 degrees F (220 degrees C).
Brush the tilapia fillets with oil on both sides, season with Creole seasoning to taste, then place into a 9x13-inch baking dish.
Bake in the preheated oven until the flesh is no longer translucent, and the fish flakes easily with a fork, about 10 minutes.
Meanwhile, melt the butter in a small saucepan over medium heat. Stir in the garlic, and cook until the garlic has softened and the aroma has mellowed, about 2 minutes. Stir in the Alfredo sauce and bring to a simmer. Reduce the heat to low, and keep warm until the fish is ready. Pour the sauce over the fish to serve. Sprinkle with additional Creole seasoning if desired.

Kitchen-Friendly View

PREP 10 mins
COOK 15 mins
READY IN 25 mins

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Reviews More Reviews

Most Helpful Positive Review

Sep 01, 2010

This is a simple yet delicious way to serve Tilapia! I had my dinner ready in about 15 minutes...which is amazing for me! I season my fillets with either Penzey's Northwoods Seasoning or Penzey's Jerk seasoning and while it's baking, I make up a quick home-made Alfredo Sauce with 1/4 cup of butter, some fresh garlic, 1/2 cup of half & half, 3/4 cup good Parmesan (grated) and a little Italian seasoning. (Just saute the garlic in the butter over med/high heat, then add the other ingredients, stirring until blended.) This recipe is definitely a keeper - thanks for a new way to serve up Tilapia!

—Westie Mom

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Most Helpful Critical Review

Nov 23, 2010

I liked the fact that the recipe is easy with ingredients found readily at home. I thought it tasted good, but not great.

—NEERONDOGS

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332 Ratings

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Jun 14, 2010

This recipe is FANTASTIC. I'm sure it's wonderful with the Creole seasoning but I can't eat spicy food so I used Johnny's Seasoning instead. When the sauteed garlic was just right I added some raw shrimp and cooked them until they were almost done, added the Alfredo sauce and heated it throughly. By the time the sauce was ready to top the fish the shrimp were perfectly cooked. Who needs to go out to eat. This is fare fit for a king.

—lakelady

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Jun 28, 2010

Out of the 10 recipes I have tried on this site this is my favorite. I used the roasted red pepper alfredo instead of regular alfredo and it was amazing.

—grmaka2

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Feb 09, 2011

OMG...this just works!!! I was a bit hesitant to top my beloved tilapia with alfredo sauce. I am so glad I did as it takes it from wonderful to amazing! I bake my tilapia the same way, but have never added a topping. I did take Westie Mom's advice and made my own alfredo sauce as I don't care for the jarred stuff. I followed her recipe for the sauce which is: 1/4 C butter, fresh minced garlic, 3/4 C parmesan cheese, 1/2 cup half and half and a bit of Italian seasoning. It was perfect! I actually used 2 T fat free half and half and 2 T heavy cream because this is what I had. Do yourself a favor and make this sauce! You only need a couple tablespoons for each piece of fish so it is worth the splurge! Thanks for a great recipe!

—Mimi2Five

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Sep 27, 2010

i used to work at ruby tuesday so i have had the new orleans seafood many many times! and have served it 100s of times. and this looked and tasted so much like it. it was delicious!! and really easy to make. i followed the recipe exactly. and used classico low calorie alfredo sauce! yum yum yum

—TiffinyRae

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Jul 01, 2010

Very Very Tasty! I did make my own alfredo sauce for this because jared ones are just not very good. This was gobbled up by all three of my children. It has been put on the "make again" list!

—MOUNTAINJENN

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Jul 22, 2010

I was a little worried about the alfredo with fish, but it was de-lish! Wish I had some broccoli or asparagas to go with it though, I think that would have really complimented the dish!! Thanks for a great meal!

—Goobeysgirl

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Nutrition

Calories
435 kcal
22%

Carbohydrates
4.4 g
1%

Cholesterol
89 mg
30%

Fat
35 g
54%

Fiber
0.2 g
< 1%

Protein
26.3 g
53%

Sodium
1089 mg
44%

* Percent Daily Values are based on a 2,000 calorie diet.

Nutritional Information

Garlic Alfredo Tilapia

Serving Size: 1/4 of a recipe
Servings Per Recipe: 4
Amount Per Serving
Calories: 435
Calories from Fat: 315

% Daily Value *
Total Fat 35g 54 %
Saturated Fat 13.7g 69 %
Cholesterol 89mg 30 %
Sodium 1089mg 44 %
** Potassium 498mg 14 %
Total Carbohydrates 4.4g 1 %
Dietary Fiber 0.2g < 1 %
Protein 26.3g 53 %
** Sugars 2g
** Vitamin A 8 %
** Vitamin C 4 %
** Calcium 5 %
** Iron 3 %
** Thiamin 9 %
** Niacin 36 %
** Vitamin B6 29 %
** Magnesium 13 %
** Folate 3 %

* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
** Nutrient information is not available for all ingredients. Amount is based on available nutrient data.
(-) Information is not currently available for this nutrient. If you are following a medically restrictive diet, please consult your doctor or registered dietitian before preparing this recipe for personal consumption.