Garlic Alfredo Tilapia Recipe -
Garlic Alfredo Tilapia Recipe
21 Photos
Garlic Alfredo Tilapia
Make this popular restaurant dish from scratch--it's easy and so tasty. See more
  • READY IN 25 mins

Garlic Alfredo Tilapia

Recipe by  

"My version of Ruby Tuesday's New Orleans Seafood, minus the shrimp. I merged a few different recipes and came up with this. It comes pretty close! Three fillets are usually enough for my husband, my toddler, and myself. I serve this with rice and steamed broccoli, to really feel like Ruby Tuesday's recipe!"

+ Recipe Box + Shopping List + Menu Print

Ingredients Edit and Save

Original recipe makes 4 servings Change Servings
  • PREP

    10 mins
  • COOK

    15 mins

    25 mins


  1. Preheat an oven to 425 degrees F (220 degrees C).
  2. Brush the tilapia fillets with oil on both sides, season with Creole seasoning to taste, then place into a 9x13-inch baking dish.
  3. Bake in the preheated oven until the flesh is no longer translucent, and the fish flakes easily with a fork, about 10 minutes.
  4. Meanwhile, melt the butter in a small saucepan over medium heat. Stir in the garlic, and cook until the garlic has softened and the aroma has mellowed, about 2 minutes. Stir in the Alfredo sauce and bring to a simmer. Reduce the heat to low, and keep warm until the fish is ready. Pour the sauce over the fish to serve. Sprinkle with additional Creole seasoning if desired.
Kitchen-Friendly View


  • Tip
  • Aluminum foil can be used to keep food moist, cook it evenly, and make clean-up easier.

Reviews More Reviews

Most Helpful Positive Review
Sep 01, 2010

This is a simple yet delicious way to serve Tilapia! I had my dinner ready in about 15 minutes...which is amazing for me! I season my fillets with either Penzey's Northwoods Seasoning or Penzey's Jerk seasoning and while it's baking, I make up a quick home-made Alfredo Sauce with 1/4 cup of butter, some fresh garlic, 1/2 cup of half & half, 3/4 cup good Parmesan (grated) and a little Italian seasoning. (Just saute the garlic in the butter over med/high heat, then add the other ingredients, stirring until blended.) This recipe is definitely a keeper - thanks for a new way to serve up Tilapia!

Most Helpful Critical Review
Nov 23, 2010

I liked the fact that the recipe is easy with ingredients found readily at home. I thought it tasted good, but not great.

Jun 14, 2010

This recipe is FANTASTIC. I'm sure it's wonderful with the Creole seasoning but I can't eat spicy food so I used Johnny's Seasoning instead. When the sauteed garlic was just right I added some raw shrimp and cooked them until they were almost done, added the Alfredo sauce and heated it throughly. By the time the sauce was ready to top the fish the shrimp were perfectly cooked. Who needs to go out to eat. This is fare fit for a king.

Jun 28, 2010

Out of the 10 recipes I have tried on this site this is my favorite. I used the roasted red pepper alfredo instead of regular alfredo and it was amazing.

Feb 09, 2011

OMG...this just works!!! I was a bit hesitant to top my beloved tilapia with alfredo sauce. I am so glad I did as it takes it from wonderful to amazing! I bake my tilapia the same way, but have never added a topping. I did take Westie Mom's advice and made my own alfredo sauce as I don't care for the jarred stuff. I followed her recipe for the sauce which is: 1/4 C butter, fresh minced garlic, 3/4 C parmesan cheese, 1/2 cup half and half and a bit of Italian seasoning. It was perfect! I actually used 2 T fat free half and half and 2 T heavy cream because this is what I had. Do yourself a favor and make this sauce! You only need a couple tablespoons for each piece of fish so it is worth the splurge! Thanks for a great recipe!

Sep 27, 2010

i used to work at ruby tuesday so i have had the new orleans seafood many many times! and have served it 100s of times. and this looked and tasted so much like it. it was delicious!! and really easy to make. i followed the recipe exactly. and used classico low calorie alfredo sauce! yum yum yum

Jul 01, 2010

Very Very Tasty! I did make my own alfredo sauce for this because jared ones are just not very good. This was gobbled up by all three of my children. It has been put on the "make again" list!

Jul 22, 2010

I was a little worried about the alfredo with fish, but it was de-lish! Wish I had some broccoli or asparagas to go with it though, I think that would have really complimented the dish!! Thanks for a great meal!


Rate This Recipe

Glad you liked it! Your friends will, too:


  • Calories
  • 435 kcal
  • 22%
  • Carbohydrates
  • 4.4 g
  • 1%
  • Cholesterol
  • 89 mg
  • 30%
  • Fat
  • 35 g
  • 54%
  • Fiber
  • 0.2 g
  • < 1%
  • Protein
  • 26.3 g
  • 53%
  • Sodium
  • 1089 mg
  • 44%

* Percent Daily Values are based on a 2,000 calorie diet.

See More

About the Cook

Subscribe Today!

In Season

Not The Same Old Chicken
Not The Same Old Chicken

We have so many top-rated chicken recipes, you'll never run out of dinner ideas again.

Slow Cooker Time Savers
Slow Cooker Time Savers

Imagine dinner making itself in the slow cooker while you relax or do other things.

Subscribe Today! Only $7.99
Subscribe Today! Only $7.99

Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!

Related Videos

Garlic Alfredo Tilapia

Make this popular restaurant dish from scratch--it's easy and so tasty.

Lemon Garlic Tilapia

See how to make a mild baked fish that’s quick, healthy, and flavorful.

Easy Baked Tilapia

Prepare a healthy and delicious meal in just a handful of minutes.

Recently Viewed Recipes

Argentina  |  Australia & New Zealand  |  Brazil  |  Canada  |  China  |  France  |  Germany  |  India  |  Italy  |  Japan  |  Korea  |  Mexico

Netherlands  |  Poland  |  Quebec  |  Russia  |  SE Asia  |  United Kingdom & Ireland  |  United States